Vitex Agnus-Castus: Complete Medicinal Profile

Vitex agnus-castus, also known as chaste tree or monk's pepper, is a flowering plant native to the Mediterranean region and parts of Asia.
The medicinal properties of Vitex agnus-castus include its ability to balance hormonal fluctuations, reduce menstrual cramps, and alleviate symptoms of menopause.
The plant has been used to promote menstrual regularity, treat premenstrual syndrome, and support reproductive health in women.
Herbal preparations of Vitex agnus-castus include supplements, teas, and tinctures, which can be used to support reproductive health and alleviate symptoms of menopause and PMS.
Study of the Day
According to Plants (Basel, Switzerland), Vitex agnus-castus has been reported to undergo clinical trials mainly related to the treatment of mastalgia, menstrual bleeding problems, amenorrhea, menorrhagia, luteal insufficiency, and premenstrual syndrome.
This page analize the most important medicinal aspects of Vitex agnus-castus.
Table of Contents
Uses and Benefits
Vitex agnus-castus is used to promote overall health and wellness, and its medicinal uses have been well-documented in traditional medicine for centuries.
This plant has been shown to be beneficial in regulating menstrual cycles and alleviating symptoms of premenstrual syndrome (PMS), such as mood swings, bloating, and breast tenderness.
Additionally, vitex agnus-castus has been found to have a positive impact on fertility, as it helps to regulate ovulation and increase the chances of conception.
By improving sleep quality, reducing stress and anxiety, and boosting the immune system, vitex agnus-castus can also contribute to a range of other health benefits, including weight management, improved mood, and enhanced energy levels.
The health benefits of Vitex agnus-castus are listed below.
- Relieves menstrual cramps: Vitex agnus-castus has been shown to reduce menstrual cramps and other symptoms associated with pms.
- Regulates menstrual cycle: This plant is known to help regulate menstrual cycles and improve fertility in women with irregular periods.
- Reduces anxiety and stress: Vitex agnus-castus contains compounds that have a calming effect on the nervous system, reducing anxiety and stress.
- Improves sleep quality: It has been found to promote relaxation and improve sleep quality, which is essential for overall health and well-being.
- Supports fertility and pregnancy: Vitex agnus-castus is often used to support fertility and pregnancy, particularly in cases of irregular ovulation.
- Reduces hot flashes and night sweats: It has been used to alleviate symptoms associated with menopause, such as hot flashes and night sweats.
- Improves mood and reduces depression: The plant contains compounds that have a positive effect on mood, reducing symptoms of depression and anxiety.
Here are the best health benefits of Vitex agnus-castus.
Actions
Vitex agnus-castus has been found to exhibit a range of therapeutic actions, including anti-inflammatory, antioxidant, and nervine properties, which can impact the endocrine system, nervous system, and gastrointestinal system.
It is also known to possess antispasmodic, antiseptic, and anti-viral actions that can affect the reproductive system, immune system, and skin.
Additionally, this plant has been reported to have adaptogenic, estrogen-regulating, and progestogenic effects that can influence the endocrine system, reproductive system, and nervous system.
The phytochemicals present in Vitex agnus-castus also exhibit antimicrobial, hepatoprotective, and vasodilatory actions that can impact the skin, digestive system, and cardiovascular system.
The therapeutic actions of Vitex agnus-castus are listed below.
- Antispasmodic: Helps to relieve muscle spasms and cramps, particularly in the menstrual cycle.
- Nervine: Has a sedative effect on the nervous system, calming anxiety and stress.
- Antioxidant: Protects cells from oxidative damage and inflammation, promoting overall health and well-being.
- Hormone regulator: May help regulate hormonal imbalances, particularly in women, and alleviate symptoms of pms.
- Uterine stimulant: Helps to stimulate uterine contractions, making it useful for inducing labor or improving menstrual flow.
- Antifungal: Has antifungal properties that help combat fungal infections, such as yeast infections.
- Emmenagogue: Helps to stimulate menstrual flow and alleviate menstrual cramps and other symptoms.
Constituents
Vitex agnus-castus has been found to contain a variety of bioactive constituents, including flavonoids such as vitexin and isovitexin, which have antioxidant and anti-inflammatory properties, helping to protect cells from damage and reduce inflammation in the body.
The plant is also rich in iridoid glycosides like agnuside, aucubin, and secologanin, which exhibit antimicrobial, antiviral, and antispasmodic activities, making them effective against infections and promoting muscle relaxation.
Tannins, such as vitexin-4'-O-glucoside, are also present, displaying astringent and antiseptic properties, while phenolic acids like caffeic acid and ferulic acid have been shown to possess antioxidant and anti-inflammatory effects, protecting against oxidative stress and inflammation.
Additionally, the plant contains coumarins, including scopoletin and umbelliferone, which have been found to exhibit sedative and anti-inflammatory properties, promoting relaxation and reducing inflammation.
The bioactive constituents of Vitex agnus-castus are listed below.
- Tannins: A type of polyphenol that contributes to the plant's astringent and antimicrobial properties.
- Flavonoids: A class of plant compounds known for their antioxidant and estrogen-modulating activities.
- Iridoids: A type of secondary metabolite that has been shown to have anti-inflammatory and antioxidant effects.
- Agnuside: A unique iridoid glycoside that is believed to be responsible for the plant's hormonal balancing effects.
- Vitexin: A flavonoid compound with antioxidant and estrogen-modulating properties.
- Acteoside: A phenylethanoid glycoside with antioxidant and anti-inflammatory effects.
- Carnosol: A phenolic diterpene with antioxidant and anti-inflammatory properties.
Parts
The most commonly used parts of Vitex agnus-castus are its flowers, leaves, and berries.
The flowers are primarily used to treat menstrual disorders, menopausal symptoms, and to balance hormonal imbalances, while also being used to treat anxiety, insomnia, and restlessness.
The leaves are used to treat a variety of health issues, including skin conditions, wounds, and as a treatment for fever and inflammation.
The berries, which are not commonly used due to their toxicity, are sometimes used in herbal medicine to treat conditions such as epilepsy, but their use is highly discouraged and should only be done under the guidance of a qualified healthcare professional.
The following table displays the most used parts of of Vitex agnus-castus and examples of ailments they help cure.
Parts | Ailments |
---|---|
Flowers | Menopausal symptoms, premenstrual syndrome, menstrual cramps |
Leaves | Gastrointestinal issues, inflammatory conditions, antimicrobial properties |
Fruits | Diarrhea, constipation, fever |
Stems | Respiratory issues, antiviral properties, antioxidant properties |
Preparations
Vitex agnus-castus most common herbal preparations are infusions, tinctures, and capsules, which are utilized for various health purposes.
Infusions, often referred to as teas, are used to alleviate menstrual cramps, hot flashes, and stress, while also being employed as a natural remedy for anxiety, insomnia, and menopausal symptoms.
Tinctures, which are concentrated extracts of the plant, are commonly used to treat hormonal imbalances, acne, and to promote relaxation and reduce stress levels, while also being employed as a natural remedy for PMS symptoms and to support fertility.
Capsules, containing the dried herb or its extracts, are often used to support adrenal function, regulate menstrual cycles, and to alleviate symptoms of menopause, such as night sweats and mood swings.
The herbal preparations of Vitex agnus-castus are listed below.
- Infusion: A liquid herbal preparation made by steeping the dried flowers, leaves, or stems of vitex agnus-castus in hot water.
- Tincture: A concentrated herbal extract made by soaking the dried flowers, leaves, or stems of vitex agnus-castus in a solvent, such as ethanol or glycerin.
- Decoction: A liquid herbal preparation made by boiling the dried roots or stems of vitex agnus-castus in water.
- Salve: A topical herbal preparation made by infusing the dried flowers, leaves, or stems of vitex agnus-castus in a carrier oil.
- Suppository: A solid herbal preparation made by infusing the dried flowers, leaves, or stems of vitex agnus-castus in a base material, such as cocoa butter.
- Capsule: A solid herbal preparation made by filling gelatin capsules with dried vitex agnus-castus flowers, leaves, or stems.
- Tea: A liquid herbal preparation made by steeping the dried flowers, leaves, or stems of vitex agnus-castus in hot water, similar to an infusion.
Side Effects
Vitex agnus-castus side effects are typically experienced by individuals who are taking high doses or have underlying health conditions.
Common side effects include dizziness, headache, nausea, stomach cramps, diarrhea, and fatigue, as well as breast tenderness, mood swings, and changes in menstrual cycles.
Women who are pregnant, breastfeeding, or taking hormonal medications are most likely to experience these side effects, which can also include insomnia, anxiety, and restlessness.
Precautions include avoiding high doses, especially in women with hormone-sensitive conditions, such as endometriosis or fibroids, and being cautious when taking the plant with other medications that affect hormone levels.
The possible side effects of Vitex agnus-castus are listed below.
- Dizziness: Users of vitex agnus-castus may experience dizziness due to its effects on the central nervous system.
- Nausea: The herb may cause nausea in some users, especially when consumed in large doses.
- Headaches: Vitex agnus-castus can cause headaches in some individuals, possibly due to its ability to affect hormone levels.
- Fatigue: Users of vitex agnus-castus may experience fatigue or lethargy due to its sedative properties.
- Stomach upset: The herb can cause stomach upset, including diarrhea or stomach cramps, especially when consumed in large doses.
- Allergic reactions: Some users may experience allergic reactions to vitex agnus-castus, including hives, itching, or difficulty breathing.
- Interactions with medications: Vitex agnus-castus may interact with certain medications, including blood thinners, and should be used with caution by individuals taking prescription medications.